Animal Handling Across CT, SPECT, PET, MR and Optical

One of the main strengths of in vivo animal imaging is the ability to image the same animal repeatedly over time, potentially using different imaging devices such as Optical, CT, SPECT, PET, etc, while accurately comparing and co-registering the images from the various scans. However, until recently, this task has been difficult to accomplish because there was no common platform, allowing the imaging of animals in multiple systems without moving them to separate proprietary stages.

To address this challenge, TriFoil Imaging has developed its imaging systems to be compatible with both Minerve and ASI-Instruments, leading manufacturers of small animal anesthesia and reanimation equipment. Through these collaborations, TriFoil is able to supply state of the art animal cells, preparation stations and control systems, and monitoring and gating systems. The result is a powerful small animal imaging system with flexibility to meet in vivo preclinical research needs.

Minerve: Small Animal Support during Imaging


Imaging Cells for preclinical imaging systems are designed to provide important support functions to the animal during the preparation stage and throughout the imaging process. Specifically, the system provides transfer of anesthetic gas, digitally controlled heating, as well as providing a pathogen free environment for immunocompromised animals. The imaging chamber enables precise repeatable positioning of the animal. The remote controlled gas anesthesia and heating control systems maintain the animal under a constant level of sedation at normal physiological temperature during the preparation and imaging process.

Separate preparation stations are available to allow for preparation of the study animal and placement in the imaging cell prior to transfer to an imaging system. The Animal 
minerventmi2Preparation Station can be connected to the optional flow control module for the supply and extraction of anesthetic gas. The system is also equipped with a thermo exchanger that can be linked to the temperature regulation unit to control the temperature of heated air flowing through the bed.


A Monitoring Acquisition Module is available integrated into the Technical Support Unit or as a standalone module, the acquisition module allows for direct interfacing with all imaging cell holders. All monitoring wires, tubes and sensors used for tracking of physiological data are contained within the module, enabling neat, easy hardware configuration with less mechanical and electromagnetic sensitivity.

ASI Instruments: Manage Small Animals Across CT, PET, SPECT, MRI and Optical



asilogo1ASI-Instruments has developed a multiple component, patented, technology for high throughput preclinical imaging in a multi-modality animal research lab. ct120wtrifoilCreated to solve the persistent issues associated with multi-modality imaging, easy and quick loading of the animal onto the bed, and a patent methodology for transporting and interfacing theanimal, in a repeatable manner (better than 50 microns) to a variety of different scanner/modalities including CT, PET, SPECT, MRI and Optical (FTM). One of the advancements is the patented coupling system which allows for the bed to be interface to any research tool if given the proper positioning receive assembly. ASI's instrument is the new way to handle, contain and load your animals for research.

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